Celastrol CAS 34157-83-0

CAS:34157-83-0

Molecular Formula:C29H38O4

Molecular Weight:450.61

EINECS:636-472-5

Mashoko anoreva zvakafanana:CELASTROL(SH); CELASTROL; Celastrol (Tripterin); CELASTROL(P)(KODA FANA); (20R) -3-Hydroxy-2-oxo-24-nor-D:A-friedoolean-1(10),3,5,7-tetren-29-oic acid; 2-Oxo-3-hydroxy-24-norfriedela-1 (10), 3,5,7-tetraene-29-oic acid; 2-Oxo-3-hydroxy-24-norfriedelane-1(10),3,5,7-tetraene-29-oic acidCelasterol

Siya Mharidzo Yako

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Chii chinonzi Celastrol CAS 34157-83-0?

Celastrol haina kunyungudika mumvura, soluble mu dimethyl sulfoxide uye anhydrous ethanol. Yakatorwa kubva kune anti-cancer inoshanda zvinorimwa muzvirimwa zvakaita seKutinhira Mwari Muzambiringa uye South Snake Vine mumhuri Celastraceae. Inoshanda proteasome inhibitor, yakasimbiswa kukurudzira cancer cell apoptosis nekudzivisa basa reproteasome.

Tsanangudzo

Item	Tsanangudzo
Boiling point	645.7±55.0 °C(Zvakafanotaurwa)
Density	1.2
Melting point	219-230°C
pKa	4.78±0.70(Zvakafanotaurwa)
λmax	424nm(MeOH)(lit.)
Kuchengetedza mamiriro	-20°C

Application

Celastrol inoshandiswa pakugadzirisa zvinyorwa / chiziviso / zviedzo zvemishonga, etc. Pharmacological effects: Iine yakasimba antioxidant properties, anti-cancer angiogenesis effects, uye anti rheumatoid effects. Inoshanda proteasome inhibitor, yakasimbiswa kukurudzira cancer cell apoptosis nekudzivisa basa reproteasome.