Metronidazole CAS 443-48-1

CAS:443-48-1

Molecular Formula:C6H9N3O3

Molecular Weight:171.15

EINECS:207-136-1

Mashoko anoreva zvakafanana:TIMTEC-BB SBB001486; 1-(2-Hydroxy-1-ethyl) -2-methyl-5-nitroimidazole; 1-(2-hydroxyethyl) -2-methyl-5-nitroimidazole; 1-(beta-Hydroxyethyl) -2-methyl-5-nitroimidazole; 1-(beta-Oxyethyl) -2-methyl-5-nitroimidazole; 1H-Imidazole-1-ethanol, 2-methyl-5-nitro-; 1H-Imidazole-1-ethanol,2-methyl-5-nitro-; 1-Hydroxyethyl-2-methyl-5-nitroimidazole; 2-(2-Methyl-5-nitro-1H-imidazol-1-yl) ethanol; 2-Methyl-1- (2-hydroxyethyl) -5-nitroimidazole

Siya Mharidzo Yako

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Chii chinonzi Metronidazole CAS 443-48-1?

Metronidazole ichena kana zvishoma yellow crystalline kana crystalline upfu; Pane kakunhuwirira, kaine kuvava uye munyu zvishoma. Inonyungudika zvishoma mu ethanol, inonyungudika zvishoma mumvura kana chloroform, uye yakanyanya kunyungudika zvishoma muether. Metronidazole initrogen-ine heterocyclic komboni ine alkalinity uye kushomeka kwemvura. Zvinoenderana neiyo prodrug musimboti, metronidazole inogadzirwa kuita potassium phosphate ester, iyo inowedzera kunyungudika kwayo mumvura uye inogona kushandiswa semushonga wejekiseni.

Tsanangudzo

Item	Tsanangudzo
Boiling point	301.12°C (yakaomarara fungidziro)
Density	1.3994 (yakaomarara fungidziro)
Melting point	159-161 °C (lit.)
pKa	pKa 2.62(H2O,t =25±0.2,
Kuchengetedza mamiriro	2-8°C

Application

Metronidazole ine simba rinorwisa mabhakitiriya kune akawanda anaerobic bacteria uye rinoshandiswa kurapa amoebiasis, trichomoniasis, uye anaerobic bhakitiriya utachiona. Inoshandiswawo kurapa vaginal trichomoniasis uye yakashandiswa kurapa intestinal uye extraintestinal amoebiasis kubva 1970. Kushanda kwayo kwakanyanya, huturu hushoma, uye hunoshandiswa zvakanyanya. Iine mutagenic uye teratogenic mhedzisiro pakuedza mhuka.