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I. Kushanda Kwemishonga Inorwisa Utachiona Hwakawanda Husina Maonero

5-Chloro-2-methyl-4-isothiazolin-3-one (CMIT), ine fomura yemamorekuru C₄H₄ClNOS uye huremu hwemamorekuru hwe149.6, inomira seimwe yemakomputa eisothiazolinone anozivikanwa uye anovimbwa nawo muindasitiri yekuchengetedza pasi rose. Iine chiyero cheBook Index che10—chiyero chepamusoro chekuchengetedza uye kuvimbika—CMITyakazvisimbisa senzira yekudzivirira hutachiona hwemazuva ano kuburikidza nemashandisirwo akasiyana-siyana emaindasitiri.

Pakutanga yakagadzirwa uye yakatengeswa naRohm naHaas pasi pezita rekuti Kathon™, CMIT inowanzo shandiswa sechinhu chakakosha chemusanganiswa we3:1 neMethylisothiazolinone (MIT). Musanganiswa uyu une simba unoonekwa seimwe yemishonga yeBroad-Spectrum Biocides inodhura uye inoshanda inowanikwa mumusika wepasi rose. CMIT inozivikanwa nekushanda kwayo kwakasiyana-siyana, ichidzivirira kukura kwebhakitiriya (Gram-positive neNegative), fungi, mbiriso, uye algae. Simba rayo riri mu bioactive sulfur moiety yayo, iyo inooxidize residues dzine thiol mumasero e microbial, ichikanganisa mapuroteni nema enzymes avo uye pakupedzisira zvichikonzera kufa kwemasero nekukurumidza. Iyi electrophilic reaction inotarisa nzira dzakakosha dze metabolic, ichivimbisa kuti tupukanana tusingakwanise kukura nekukurumidza - mukana mukuru kupfuura mamwe ma preservative chemistry akawanda. Pahuwandu hwakaderera se150 ppm, inogona kudzvinyirira kukura kwebhakitiriya zvachose, uye pa125 ppm, inodzivisa mbiriso nekuumbwa zvizere, ichivimbisa kugadzikana kwechigadzirwa uye kuchengetedzeka panguva yekuchengetedza nekushandisa.

II. Mashandisirwo Emaindasitiri Anoshandiswa Pakuchinja-chinja Muzvikamu Zvikuru

Kubatsira kwe5-Chloro-2-methyl-4-isothiazolin-3-imweInopararira muzvikamu zvakasiyana-siyana zvemaindasitiri, ichipa dziviriro yakakosha munzvimbo dzakaoma uko kusvibiswa kwehutachiona kunokonzera njodzi huru kumhando yezvigadzirwa uye kuchengetedzeka kwekushanda.

Mukurapa mvura mumaindasitiri, CMIT inoshandiswa zvakanyanya mukuchenesa mvura inotonhorera, kugadzirisa mvura yakasviba, uye kugadzira masisitimu emvura kudzora kukura kwehutachiona nekudzivirira biofouling. Biofilms inogona kuderedza zvakanyanya kushanda kwekupisa uye kukurumidzisa ngura mumapaipi nemidziyo. Nekubvisa nharaunda idzi dzehutachiona zvinobudirira, CMIT inovimbisa kushanda zvakanaka uye kugara kwenguva refu kwezvivakwa zvakaoma zvemaindasitiri, ichideredza mari yekugadzirisa uye nguva yekushanda. Muindasitiri yekupenda,CMITchinhu chakakosha pakuchengetedza mukati memuchina, kuchengetedza pendi dzinobva mumvura, emulsions, uye manamatisi kubva mukuora kwehutachiona panguva yekuchengetwa. Pasina kuchengetedzwa kwakakwana, zvigadzirwa izvi zvinogona kukura nemabhakitiriya nefungus izvo zvinokonzera kunhuwa, kuchinja kwe viscosity, uye kutadza kwechigadzirwa pakupedzisira. Chikamu chemafuta negasi chinovimba neCMIT kurwisa kusvibiswa kwehutachiona muzvinwiwa zvekuchera uye masisitimu emafuta. Mabhakitiriya anoderedza sulfate anogona kugadzira hydrogen sulfide, zvichikonzera kusviba kwezvirongo uye ngura yakanyanya yemidziyo yesimbi. Pamusoro pezvo,CMITinoshanda senzira yekuchengetedza zvinhu inoshanda mumasipo, sipo dzekugezesa, nezvimwe zvinoshandiswa pakuchenesa dzimba, ichidzivirira kukura kwehutachiona hunogona kukanganisa kunaka kwechigadzirwa.

III. Basa Rinokosha Mukutarisira Munhu Nemiganhu Yakakomba Yekutonga

Panguva iyoCMITmushonga unoshanda zvikuru, kushandiswa kwawo mukuchengetedza munhu kunotarisirwa pasi pemutemo wakasimba nekuda kwekugona kwawo kunzwisiswa. Muindasitiri yezvizoro, unoshandiswa kakawanda muzvigadzirwa zvekusuka senge shampoos, conditioners, uye body washes, uko simba rawo rekuchengetedza rinobatsira kuchengetedza kunaka kwechigadzirwa. Zvisinei, kushandiswa uku kunoda kunyatsojeka, sezvo CMIT inyanzvi inozivikanwa yekudzivirira ganda inogona kukonzera allergic contact dermatitis kuvanhu vane chirwere ichi.

Pasi peCosmetic Safety Technical Specification (2015 Edition), musanganiswa we3:1 weCMIT/MIT unobvumirwa chete muzvigadzirwa zvekuzora zvinoshambidzwa zvine huwandu hwakanyanya hwe0.0015% (15 ppm). Kushandiswa kwakaderera uku kunoratidza simba guru remushonga uyu—kunyangwe pahuwandu hushoma kudaro, unochengetedza zvakakwana kubva muzvinhu zvakasiyana-siyana zvinosvibisa. Kupfuura muganho uyu kunokonzera njodzi huru dzehutano, kusanganisira kutsvuka kweganda, kuvaviwa, mapundu, uye allergic reactions. Mabasa emutemo achangoburwa munzvimbo dzakasiyana-siyana anoratidza kukosha kwekutevedzera mitemo iyi yekuchengetedza. Vagadziri vanofanirwa kuchengetedza mitemo yakasimba yekudzora mhando, masisitimu chaiwo ekuyedza, uye kuyedzwa kwakakwana kwezvinhu kuti vave nechokwadi chekuchengetedzwa kwevatengi uku vachishandisa simba rayo rekuchengetedza.

IV. Kugadzikana, Kuenderana, uye Mabhenefiti Ekuumbwa

Kupfuura simba rayo rekurwisa utachiona,CMITinopa mabhenefiti akakosha kubva pakuona kwekugadzira. CMIT inoratidza kugadzikana kwakanaka mumamiriro akasiyana-siyana epH, ichichengetedza kushanda kwayo pakati pepH 2 ne9, zvichiita kuti ive yakakodzera mhando dzakasiyana dzezvigadzirwa kubva pakugadzira acidic kusvika ku neutral emulsions uye ma industrial fluids ane alkaline zvishoma. Kugadzikana kwayo pakupisa kunoita kuti irambe ichishanda kunyangwe munzvimbo dzekugadzirisa uko tembiricha yakakwira inosangana nayo.

CMITInoratidzawo kubatana kwakanaka nezvinhu zvinonyanya kushandiswa mukugadzira, zvinosanganisira nonionic, anionic, uye amphoteric surfactants, pamwe chete nemapolymer akasiyana-siyana, thickeners, uye emulsifiers. Kubatana uku kunoderedza njodzi yekudyidzana kusingadiwe kunogona kukonzera kusagadzikana kwekugadzira kana kudzikira kwekushanda kwekuchengetedza. Kusiyana nezvimwe zvinochengetedza zvechinyakare zvinogona kuita nezvimwe zvikamu kuti zvigadzire precipitates, CMIT inobatanidzwa zvakanaka mumafomu akaomarara pasina kukanganisa hunhu hwerunako senge ruvara, hwema, kana magadzirirwo. Uyezve, CMIT haibatsiri mukuburitswa kwe formaldehyde kana kuti ine halogenated solvents, zvichiita kuti ive sarudzo inogamuchirika kune nharaunda kana tichienzanisa nedzimwe tekinoroji dzekare dzekuchengetedza.

 V.Basa Rinokosha reCMIT muMaitiro Ekuchengetedza Mazuva Ano

Pasinei nezvirambidzo zvemutemo zvine chekuita nekushandiswa kwayo,CMITinoramba iri chishandiso chakakosha mudura remugadziri wezvinhu. Kubudirira kwayo pamutengo kusingaenzaniswi—kuchengetedza kwakasimba pahuwandu hwakaderera zvikuru—kunoita kuti ive yakachipa zvikuru kupfuura dzimwe nzira dzekuchengetedza dzinoda huwandu hwakakwira hwedosi. Kukurumidza kwayo kuuraya kunopa dziviriro nekukurumidza kubva kuzviitiko zvekusvibiswa, izvo zvinonyanya kukosha munzvimbo dzekugadzira uko zvigadzirwa zvakawanda zviri munjodzi panguva yekugadzira uye kurongedza. Kushanda kwayo kwakafara kunovimbisa dziviriro yakakwana kubva kumarudzi ese etupukanana tunowanzo tyisidzira zvigadzirwa zvemaindasitiri, zvichiita kuti nzira dzekuchengetedza dzive nyore.

Kutarisira,CMIT'sBasa guru mukuchengetedza maindasitiri rinotarisirwa kuramba riripo, kunyanya mukushandiswa kusiri kwekushongedza uko kushanda kwayo kwepamusoro uye mabhenefiti emutengo zvichiri zvisingaenzaniswi. Kutsvagurudza kuri kuenderera mberi mune matekinoroji matsva ekugadzira uye masisitimu ekudzivirira kunogona kuwedzera kuchengetedzeka kwayo, zvichiita kuti irambe ichishandiswa uku ichigadzirisa matambudziko matsva ehutano nezvakatipoteredza. Sezvo indasitiri yekuchengetedza ichifambira mberi kune mhinduro dzinogara kwenguva refu, CMIT ingangoramba iri panzvimbo yayo semushonga wekutanga wehutachiona hwehutachiona - uyo unoenzanisa kushanda kwayo kwakanyanya nekuzvipira kwakasimba kukuchengetedza uye mutoro wekutonga.