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Nokuda kwekuchengetedza kweganda kunobudirira, hongu, hazvidzivisiki kuva neimwe pfungwa yezvigadzirwa, kwete chete kukurudzirwa kwechigadzirwa, asiwo zvigadzirwa zvechigadzirwa. Nhasi ngatitaure nezve "carnosine" yezvigadzirwa zvezvigadzirwa zvekuchengetedza ganda.

Chii chinonzi 'Carnosine'
Carnosine idipeptide inoumbwa ne beta-alanine uye L-histidine, iyo ine yakakwira yemukati mumhasuru uye mabhuroko ehuropi. Carnosine ine yakakwira antioxidant zvimiro uye inogona kuchenesa mahara radicals mumuviri.

Iyo 'carnosine' inoshanda sei
Carnosine inogona kuwedzera kupikisa kweganda, kuchengetedza hudiki hwemaseru nekuchengetedza kuita kwemasero mune yakazara spectrum bhendi uye yemahara radical mamiriro, kukurudzira kugadzirwa kwe collagen, uye kuchengetedza ganda rakasimba.

Basa re 'carnosine'
Carnosine inogona kuwedzera kupikisa kweganda, kuchengetedza hudiki hwemaseru nekuchengetedza kuita kwemasero mune yakazara spectrum bhendi uye yemahara radical mamiriro, kukurudzira kugadzirwa kwe collagen, uye kuchengetedza ganda rakasimba. Mamiriro emakemikari eL-carnosinendiko kuumbwa kwe beta-alanine uye L-histidine kuburikidza nekuita kwecarnosine synthase. Carnosine ine tarisiro yakafara yekushandiswa muminda yemishonga, hutano hwehutano, uye hutsanana nekuda kweiyo antioxidant zvimiro, mahara radical scavenging mhedzisiro, chelation ine shanduko simbi, neuroprotection, kukurudzira kuporesa maronda, uye anti-kuchembera.

1. Kushandiswa kwecarnosine muindasitiri yezvekudya
Chinhu chikuru chemafuta muzvokudya musanganiswa wemafuta akasiyana-siyana ane acid glycerides. Nekuda kwemahara radical reaction yeunsaturated fatty acid glycerides panguva yekuchengetera, peroxides uye anonhuwirira aldehydes kana carboxylic acid ane mapfupi kabhoni cheni anogadzirwa. Naizvozvo, kudya chikafu chine mafuta peroxides kunosimudzira lipid peroxidation mumiviri yevanhu uye kukonzera zvirwere zvakasiyana. Naizvozvo, butylated hydroxyanisole, dibutylated hydroxytoluene, propyl gallate, nezvimwewo zvinowanzoshandiswa mukugadzira chikafu uye kuchengetedza kudzivirira mafuta peroxidation, asi kushanda kwavo kuchaderedzwa mukupisa kwekugadzira chikafu, uye ine imwe huturu. L-carnosine haigoni kungodzivisa zvinobudirira mafuta oxidation, asiwo ine kuchengetedzwa kwepamusoro uye mabasa ehutano hwehutano. Naizvozvo, L-carnosine yakakosha uye yakakodzera chikafu che antioxidant.
2. Kushandiswa kwecarnosine mumishonga uye hutano hwehutano
(1) Carnosine uye Antioxidant

Carnosine haigone kushandisa imidazole mhete N atomu uye peptide bond N atomu pane histidine zvakasara kuti chelate metal ions uye inhibit iyo mafuta oxidation inokonzerwa nesimbi ions, asiwo histidine padivi cheni ye carnosine ine kugona kubata hydroxyl radicals. Inogona kuvharidzira oxidation yemafuta inokonzerwa neiyo isiri-simbi ions. Naizvozvo, senge multifunctional antioxidant active substance, carnosine inogona kugadzikana kuchengetedza cell membrane uye inonyungudika nemvura isina radical scavenger. , inogona kudzivirira peroxidation ye cell membrane. Kuenzaniswa nemamwe biological antioxidants akadai seVC, carnosine ine yakasimba antioxidant kugona. Mukuwedzera pakudzivisa peroxidation process ye cell membrane, carnosine inogonawo kudzivisa mamwe maitiro e-intracellular peroxidation reactions, kureva, carnosine inogona kuvharidzira nhanho imwe neimwe ye oxidation reaction muketani yose yeperoxidation mumutumbi. Basa rema antioxidants akadai seVC ndere kudzivirira mahara radicals kuti asapinde munyama, kureva kuti, anogona chete kudzivirira iyo yemvura peroxidation process ye cell membrane, uye hapana chavanogona kuita kune emahara radicals akapinda muchitokisi.
(2) Carnosine uye gastric ulcer

Peptic ulcer chirwere chepasi rose chisingaperi chekudya, uye izvo zvinokonzeresa maronda hazvisi kunyatsojeka pari zvino, asi pathology inotenda kuti hutsinye zvinhu (senge gastric acid, pepsin secretion, Helicobacter pylori utachiona) uye kudzivirira kana cellular Inokonzerwa ne kusaenzana kwezvinhu zvinodzivirira (mucus secretion, bicarbonate secretion, prostaglandin production). Iyo yakasikwa inodzivirira nzira yemudumbu ndeye: inoumba gobvu dhizaini yegastric mucosa inoshanda sechidziviriro chinodzivirira kuchengetedza masero ari mumucheka. Kuramba kuvharidzirwa kwemucous membrane kunodzivirira dumbu, asi kuvharidzira kwakanyanya kunogona kukonzera gastric ulcers. Zvidzidzo zvakawana kuti zinc-carnosine inotorwa nechikafu inogona kunyatso kudzivirira maronda, inogona kunyatso chengetedza kuvimbika kwemudumbu uye maitiro ayo ekudzivirira echisikigo, izvi zvinokonzerwa necarnosine's antioxidant properties, membrane stabilization, regulation Pharmacological properties of immune and repair tissues. Maererano nemakiriniki ekuedzwa, mushure mekutora zinc-carnosine kwemavhiki masere, 70% yevarwere vakatora mushonga vakaratidza kuvandudzwa kukuru, uye 65% yezvironda zvepadumbu zvakavandudzwa kuburikidza negastroscopy.
(3) Carnosine uye immune regulation

Immune mhinduro ibasa remuviri rinochengetedza homeostasis uye rinodzorwa ne physiologically inoshanda zvinhu muzvisikwa zvipenyu. Immunomodulators inoreva kurapwa kwekirasi yezvirwere zvinokonzerwa nekudzivirira muviri, uye inoshandiswa kudzoreredza mhinduro yezvirwere zvemuviri, inhibit kuderera kwayo kusingaite kana kudzvanyirira mhinduro yayo nekukurumidza. Mazhinji ema immunomodulators aripo anogadzirwa nemakemikari synthesis nzira, ine imwe muchetura uye mhedzisiro. Zvidzidzo zvakaratidza kuti carnosine ine immunomodulatory basa, uye ndiyo yega physiologically inoshanda chinhu chakawanikwa kusvika parizvino chekudzivirira, uye yakashandiswa zvakanyanya mukurapa kwezvirwere zvakasiyana-siyana zvekudzivirira zvirwere uye zvirwere zvinokonzerwa nehutachiona husina kujairika.