Hydroxypropyl beta-cyclodextrin, inozivikanwawo se (2-hydroxypropyl) -β-cyclodextrin, iatomu rehydrogen riri mumapoka e2-, 3-, uye 6-hydroxyl eglucose residues muβ-cyclodextrin (β-CD) inotsiviwa nehydroxypropyl kuita hydroxypropoxy. HP-β-CD haina chete mhedzisiro yakanaka pamakemikari akawanda akaita seβ-CD, asiwo ine zvakanakira zvekunyungudika kwemvura yakawanda uye kuvandudza mwero wekusunungurwa uye kuwanikwa kwemishonga yakavharirwa mumuviri. Pamusoro pezvo, HP-β-CD imushonga unobatsira une data rakawanda rekuchengetedza rakaunganidzwa uye hapana mhedzisiro yakaipa. HP-β-CD inogona zvakare kushandiswa semudziviriri wemapuroteni uye stabilizer.
Hydroxypropyl beta-cyclodextrin ipfu chena kana chena isina chimiro kana kristalline; Hainhuhwi, inotapira zvishoma; Inonyungudutsa hunyoro zvakanyanya. Chigadzirwa ichi chinonyungudika nyore mumvura, chinonyungudika nyore nyore mumethanol, ethanol, chisinganyungudike muacetone, trichloromethane.
Kunyunguduka kwehydroxypropyl-B-cyclodextrinMvura yakanaka kwazvo, uye mwero wekutsiva we4 zvichikwira unogona kusanganiswa nemvura chero chikamu chipi zvacho, uye unogona zvakare kunyungudutswa mu50% ethanol nemethanol. Ine hygroscopicity yakati wandei. Asi kushanda kwepamusoro uye kushanda kwehemolytic kwakaderera. Haina kutsamwisa tsandanyama uye chinhu chakanakira solvent enhancer uye mushonga wekurapa wekubaiwa jekiseni.
Chii chinoshandiswa pakushandisa hydroxypropyl beta-cyclodextrin?
Mumunda wezvekudya nezvinonhuwira
Hydroxypropyl beta-cyclodextrin inogona kuvandudza kugadzikana uye kushanda kwenguva refu kwemamorekuru ezvekudya, kufukidza kana kugadzirisa hwema hwakaipa uye kuravira kwemamorekuru ezvekudya, uye kuvandudza maitiro ekugadzira uye kunaka kwechigadzirwa.
Muzvizoro
Zvinhu zvakagadzirwa nezvizoro zvinogona kushandiswa sezvinodzivirira, zvinosanganisa ganda, zvinobvisa zvinonhuwira, nezvimwewo, izvo zvinogona kuderedza kukurudzirwa kwemamorekuru eorganic muzvizoro paganda nemukati meganda, kuwedzera kugadzikana kwezvinhu zvinoshanda, uye kudzivirira kuvhiringidzika uye oxidation yezvinovaka muviri. Zvine hygroscopicity yakati wandei.
Mumunda wemishonga
Hydroxypropyl beta-cyclodextrinInogona kuvandudza kunyungudika kwemishonga isinganyungudike mumvura, kuwedzera kugadzikana kwemishonga, kuwedzera kuwanikwa kwemishonga, kuwedzera kushanda kwemishonga kana kuderedza chiyero, kugadzirisa kana kudzora kumhanya kwekuburitswa kwemishonga, uye kuderedza chepfu yemishonga. Inogona kushandiswa semutakuri wemishonga inonwiwa, majekiseni, masisitimu ekutumira mishonga mudumbu (kusanganisira mucosa yemhino, rectum, cornea, nezvimwewo), masisitimu ekutumira mishonga inonyungudika kubva mumhino, mishonga inorwisa lipophilic, uye inogonawo kushandiswa semudziviriri wemapuroteni uye stabilizer.
Nguva yekutumira: Gumiguru-20-2023